What Is The Stamets Stack ?

Paul Stamets

Paul Stamets, known to some as the “Mushroom Man” and to fungi as a kindred spirit, has dedicated decades to cracking open the earthy secrets of mushrooms. Picture Stamets as a wizard of the undergrowth, conjuring visions of a world transformed by fungi. His work isn't merely scientific—it's mythic, pulsing with the primal energy of life itself. From cleaning up toxic spills to sparking neural fireworks, Stamets has revealed fungi’s dazzling potential to heal both Earth and mind. Enter the "Stamets Stack"—a bold blend of psilocybin, niacin, and Lion’s Mane, a brain-boosting concoction born from Stamets’ crusade for human and planetary health. He’s the modern-day Merlin of mushrooms, forever reshaping how we think about the mysterious power of the mycelial kingdom.

Psilocybin Micro-dose

A psilocybin microdose is a very small, sub-perceptual amount of psilocybin, typically around 0.01 to 0.03 grams, taken to gently influence the mind without inducing a full psychedelic experience. Unlike standard doses, microdosing is intended to subtly enhance cognitive function, creativity, and emotional balance, often integrating into daily life without disrupting routine. People who microdose report experiencing improved focus, reduced anxiety, and heightened insights, as the minimal psilocybin amount fosters a gentle shift in perception without overwhelming the senses. This practice has gained attention for its potential to promote mental clarity, emotional resilience, and overall well-being, allowing users to access psilocybin's benefits in a safe, sustainable way.

Lion’s Mane Fruiting Bodies

Lion’s Mane (Hericium erinaceus) fruiting bodies are the mushroom’s visible, fleshy structures, celebrated for their unique, cascading appearance and powerful health benefits. Known in traditional and modern medicine alike, Lion’s Mane fruiting bodies are packed with bioactive compounds that support brain health, particularly by promoting nerve growth factor (NGF) production, which plays a key role in brain cell growth and repair. This mushroom is frequently used to enhance cognitive function, memory, and focus, making it a popular choice in nootropic and microdosing stacks. Unlike mycelium, which is the root-like structure of mushrooms, fruiting bodies contain the highest concentration of beneficial compounds, making them a preferred choice for maximizing Lion’s Mane’s mental and neural benefits

Niacin B3 w/ Flush

Niacin, or Vitamin B3 with a flush, is a form of Vitamin B3 known for its unique ability to widen blood vessels and enhance circulation, resulting in a temporary "flush" sensation in the skin. This flushing effect, which can feel like warmth or tingling, is due to increased blood flow, allowing Niacin to efficiently transport nutrients throughout the body. Niacin B3 is essential for converting food into energy, supporting brain function, and maintaining healthy skin and nerve function. When combined with other compounds, like Lion’s Mane or psilocybin in microdosing protocols, Niacin B3 with a flush may aid in delivering these beneficial substances more effectively across the blood-brain barrier, enhancing their effects for cognitive and neural health.

Other Protocols

Although High Vibrations recommends the Stamets Stack, given the enhanced benefits of combining Lion's Mane and Niacin with psilocybin, it’s important to find a protocol that aligns with your unique needs and goals. Microdosing is known to be extremely safe, and experimenting with different cycles can help you discover the most effective routine for your personal growth and wellness. Embrace the freedom to explore what works best for you.

The Fadiman Protocol, christened in honor of the psychedelic maestro Dr. James Fadiman, is more than a mere dosing schedule—it’s a dance with the mind’s inner eccentricities, choreographed by the "father of microdosing" himself. Picture Dr. Fadiman, part psychonaut, part sage, tinkering with sub-perceptual doses like an alchemist on the edge of discovery. His approach isn’t about blasting off into the cosmos; it’s a whisper to the psyche every third day—a rhythm designed to coax out creativity, untangle emotions, and add a splash of color to the ordinary. This protocol, much like Fadiman, tiptoes along that fine line where science meets the sublime.

Every Other Day

Take a dose every other day for a period of 4-8 weeks

After the 4-8 weeks take 2-4 weeks off

2 : 1

This protocol calls for 2 days of dosing followed by one day off and is repeated for 4-8 weeks

After the 4-8 weeks take 2-4 weeks off

Microdosing has a knack for rooting you in the here and now, like a deep, satisfying breath that settles over you. It brings an easy calm, coaxing you out of the relentless forward spin of thoughts and deadlines, back into the present moment—the only moment that truly matters. With each tiny dose, there’s a softening, a gentleness, a clarity that lets you see the world as it is: colors a bit more vivid, sounds a touch richer, sensations more grounded. Paired with a High Vibrations mocktail, you’re not just sipping a drink; you’re engaging in a mindful ritual that heightens this sense of calm, making each taste and moment feel like its own tiny adventure. You feel anchored, centered, and perfectly attuned, a peaceful pulse of consciousness that lets you savor the now.